- QUESTION
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Not all EBP projects result in statistically significant results. Define clinical significance, and explain the difference between clinical and statistical significance. How can you use clinical significance to support positive outcomes in your project? |
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| Subject | Nursing | Pages | 3 | Style | APA |
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Answer
Evidence-Based Practice Project: Hand Hygiene
Not all evidence-based practice projects can result in statistically significant results. In clinical research, study findings that are considered as statistically significant are also, in most cases, considered clinically important/significant. There are fundamental differences between clinical and statistical significance. Clinical significance is defined as the magnitude of the actual treatment effect. Clinical significance determines whether the outcome of a study will impact current medical practice or not. While clinical significance reflects the effect or impact of the study results in clinical practice, statistical significance, on the other hand, indicates the reliability of the study results (Ranganathan, Pramesh, & Buyse, 2015).
There is need to promote achievement of clinical significance in the proposed capstone change project. Capstone change project aims to use hand hygiene intervention to reduce the cost of care and risk of hospital-acquired infections, increased length of hospitalization, and reduce rate of antibiotic administration in the geriatric ward. To enhance clinical significance of the results of the proposed intervention, there is need to ensure that the actual outcomes of the change project (as provided above) are detected, objectively measured and analyzed (Ranganathan et al., 2015). Testing of the null-hypothesis and determination of the p-value would inform on whether the outcome of the study are clinically significant to inform clinical practice (Nordahl-Hansen et al., 2018).
References
Nordahl-Hansen, A., Øien, R. A., Volkmar, F., Shic, F., & Cicchetti, D. V. (2018). Enhancing the understanding of clinically meaningful results: A clinical research perspective. Psychiatry Research, 270, 801-806. https://doi.org/10.1016/j.psychres.2018.10.069
Ranganathan, P., Pramesh, C. S., & Buyse, M. (2015). Common pitfalls in statistical analysis: Clinical versus statistical significance. Perspect Clin Res [serial online], 6, 169-70. http://www.picronline.org/text.asp?2015/6/3/169/159943 This question has been answered