Evidence-Based Practice Project Paper on Diabetes

1. QUESTION
THIS IS ANOTHER PART FOR 866610, THE SAME WRITER TOO.

This week’s assignment has two parts: an EBP paper and a PowerPoint presentation. Choose a peer reviewed research article and summarize the article for the paper. The research must be current! No more than five years old at the most and, preferably, two years or less. Make sure you are choosing an original EBP or research article and not an article that is already summarizing the research. Meeting all required elements of the assignment is difficult when you are summarizing a summary! If in doubt about your article, ask! When submitting your paper to the grade book, please include a PDF of the selected article.
The PowerPoint will be a presentation of the summary of the article. Again, you only need to identify one article, summarize it, and create a PowerPoint presentation of the summary. This assignment is due by Sunday.
Please note, I cannot, per GCU policy, accept any work after Sunday at midnight. All work must be submitted by then, no exceptions!
Evidence-Based Practice Paper and Intervention
Presentation
1) Identify a research or evidence-based article that discusses a new diagnostic tool or intervention for the treatment of diabetes in adults or children.
2) Evidence-Based Practice Paper
a) In a paper of 750-1,000 words, summarize the research findings and how they can be applied to a specific patient population.
b) Prepare this assignment according to the APA guidelines found in the APA Style Guide, located in the Student Success Center. An abstract is not required.
3) Intervention PowerPoint Presentation
a) Develop a PowerPoint (6-12 slides, no larger than 2 MB) that includes the following:
i) A description of the diagnostic tool or intervention
ii) A summary of the research conducted
iii) Discussion of how the new tool or intervention may be integrated into practice
iv) Explanation of its impact on nursing
b) While APA format is not required for the body of this
assignment, solid academic writing is expected and in-text citations and references should be presented using APA documentation guidelines, which can be found in the APA Style Guide, located in the Student Success Center. You are expected to develop original slides and cite your sources. You cannot use slides obtained from slide share sites.
4) Refer to “Evidence-Based Practice Paper and Intervention PowerPoint Presentation Grading Criteria,” located in the module 5 grade book.
5) Submit the assignment to the instructor by the end of Module 5.

Based on the summary of research findings identified from the Evidence-Based Project—Paper on Diabetes that describes a new diagnostic tool or intervention for the treatment of diabetes in adults or children, complete the following components of this assignment:
Develop a PowerPoint presentation (a title slide, 6-12 slides, and a reference slide; no larger than 2 MB) that includes the following:
A brief summary of the research conducted in the Evidence-Based Project – Paper on Diabetes.
A descriptive and reflective discussion of how the new tool or intervention may be integrated into practice that is supported by sound research.
While APA format is not required for the body of this assignment, solid academic writing is expected, and in-text citations and references should be presented using APA documentation guidelines, which can be found in the APA Style Guide, located in the Student Success Center.

Subject	Nursing	Pages	4	Style	APA

Answer

Student’s Name
Institutional Affiliation
Introduction
Diabetes mellitus is one of the top ten global causes of death (WHO, 2018).
Various interventions have been discovered to manage diabetes.
Some of these are incretin-based therapies such as DPP-4 inhibitors and GLP-1R .
This presentation provides a summary of the tool as presentation in the article “Incretin-Based Therapies for Diabetic Complications: Basic Mechanisms and Clinical Evidence” by Kawanami, Matoba, Sango, and Utsunomiya (2016).
Description of The Diagnostic Tool/Intervention
The incretin-based therapies are dipeptidyl peptidase-4 inhibitors (DPP-4i) and glucagon-like peptide-1 (GLP-1) receptor (GLP-1R) agonists.
An example of DPP-4i is Exendin-4 while GLP-1 include
The interventions regulate inset function and lower glucose levels.
Summary: Research Aims/Objectives
The primary the aim of the study by Kawanami, Matoba, Sango, and Utsunomiya (2016) was to establish the various pieces of evidence from experiments and clinical trials on the use of incretin-based therapy for the treatment of diabetic complications in adults.
Summary: Methodology
The authors reviewed a variety of experimental and clinical studies which have been done on incretin-based therapy.
The focus was on the available evidence for the use of incretin-based interventions for treating diabetic nephropathy, macrovasculopathy, retinopathy, and neuropathy.
Summary: Findings
In clinical studies done on the specific impact of DPP-4 inhibitors, the results were that DPP-4 activity was high in people with type 1 and type 2 diabetes.
Upon the use of DPP-4 inhibitors, there was a presence of impaired incretin dynamics in type 2 diabetes.
The use of Saxagliptin Assessment of Vascular Outcomes Recorded in Patients with Diabetes Mellitus-Thrombolysis in Myocardial Infarction (SAVOR-TIMI 53) demonstrated that there was improved albuminuria by saxagliptin in patients with type 2 diabetes.
Findings Cont’d
It was found that DPP-4 inhibitors serve to attenuate albuminuria beyond the initial purpose of glucose-lowering.
The three periods of treatment were sitagliptin taken at 50 mg/day for four weeks, alogliptin 25 mg/day for four weeks, and sitagliptin 50 mg/day for four weeks .
Apart from the attenuating effects of the incretin-based therapies, they were also found to have anti-atherosclerotic effects.
Summary: Conclusions
Kawanami et al. (2016) concluded that incretin-based therapies are beneficial in the treatment of diabetic complications.
Although the DPP-4 inhibitors and GLP-1RA are similar regarding their pleiotropic effects, their pharmacological actions are different.
Integration Into Practice
The incretin-based therapies can be integrated to nursing practice by educating nurses on how to apply them.
Nursing professionals should be informed about the effects of the interventions and ways that they will be vital to use to diabetic patients.
In nursing, the interventions can be integrated by making them as the first options for application to patients (Ahrén, 2014).
More research should also be done to ensure that all aspects of the interventions are known before they are fully integrated.
Impact of The Tool on Nursing
Nursing practitioners will now focus on the use of incretin-based therapies as they have been found to be important therapeutic options (Ahrén, 2014).
The rates of cardiovascular complications which arise from diabetes will decrease because the interventions not only lead to the management of diabetes but also its related complications.
The nursing profession has now found tools which are not only easy to use but also whose impacts on the diabetic patients are known (Gamble et al., 2015).
Conclusion
Some of the interventions which have been introduced in the management of diabetes are incretin-based therapies such as DPP-4 inhibitors and GLP-1R
In the study by Kawanami, Matoba, Sango, and Utsunomiya (2016), the findings were that the therapies attenuate albuminuria beyond the initial purpose of glucose-lowering.
The interventions can be integrated in nursing practice to ensure reduced cases of complications arising from diabetes and proper management of the condition.

This question has been answered

References

Kawanami, D., Matoba, K., Sango, K., & Utsunomiya, K. (2016). Incretin-based therapies for diabetic complications: basic mechanisms and clinical evidence. International journal of molecular sciences, 17(8), 1223.
(2018). The top 10 causes of death. Retrieved from https://www.who.int/news-room/fact-sheets/detail/the-top-10-causes-of-death
Gamble, J. M., Clarke, A., Myers, K. J., Agnew, M. D., Hatch, K., Snow, M. M., & Davis, E. M. (2015). Incretin‐based medications for type 2 diabetes: an overview of reviews. Diabetes, Obesity and Metabolism, 17(7), 649-658.
Ahrén, B. (2014). Insulin plus incretin: a glucose-lowering strategy for type 2-diabetes. World journal of diabetes, 5(1), 40.

Appendix

Appendix A:

Communication Plan for an Inpatient Unit to Evaluate the Impact of Transformational Leadership Style Compared to Other Leader Styles such as Bureaucratic and Laissez-Faire Leadership in Nurse Engagement, Retention, and Team Member Satisfaction Over the Course of One Year