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- QUESTION
Can you write a respond to these to discussion boards?
Your peer responses must be scholarly and supportive. If you choose to respond to a peer, find an article that either supports or contradicts what they have posted. Professionally respond to them as a discussion. Per instructor
Discussion 1Hemolytic Anemia is a disorder where the red blood cells are destroyed at a faster rate than they are made(Huether & Mccance, 2017). Acquired Hemolytic Anemia is a condition you are not born with but develop later. With this type, you can create normal Red Blood Cells, but they are later destroyed. Etiologies may happen because of viral or bacterial infection, autoimmune disorders, blood cancers, and a severe reaction from a blood transfusion. Whereas, hereditary hemolytic anemia is passed down from the parent's genes to their children((Huether & Mccance, 2017). This condition can produce RBC however they do not live as long as normal blood cells. Both Acquired and Inherited Hemolytic Anemia have two mechanisms 1) Intravascular hemolysis the destruction of RBC where the contents of the cell are released in the plasma. 2) Extravascular hemolysis is the removal of red blood cells with changes to the membrane of the spleen and liver (Guolla & Chan, 2018).
References:
Guolla, L., & Chan, K. (2018). Hemolytic Anemia. Essentials of Pediatric Emergency Medicine, 178.
Huether, S. E., & Mccance, K. L. (2017). Understanding pathophysiology. St. Louis, Mo: Mosby.
Discussion 2
There are various types of anemic conditions, but the overall definition of anemia is that it is a condition in which the blood lacks enough healthy red blood cells in order to meet the body’s physiological requirements (Kishore et al., 2020). Hemolytic anemia is a disorder in which RBCs are destroyed by a specific type of antibodies, which can lead to the development of anemia. This type of anemia can be caused by inheriting the disorder, primary, which is due to idiopathic cause or secondary, which is due to and the underlying cause. A condition that is considered idiopathic when the cause is unknown and underlying causes could be connective tissue disorders, renal failure, hematological disorders, hematological malignancies in tuberculosis, HIV infection, and miscellaneous causes (Habiba, Ilyas, Sijjeel, Tabassum, & Fatima, 2020). According to Schuurman et al. (2015), sickle cell anemia is an inherited autosomal recessive disorder characterized by the production of abnormal hemoglobin S (HbS) within the erythrocytes. HbS is formed by a genetic mutation in which the amino acid valine replaces glutamic acid. This type of disorder is caused by a mutation in the gene, which is inherited by at least one of the parents. The pathophysiological mechanism shared by hemolytic and sickle cell anemia is that they could both be inherited and both destruct/break down red blood cells, hemolysis, which can lead to severe pain.References:
Habiba, U., Ilyas, A., Sijjeel, F., Tabassum, G., & Fatima, S. (2020). Causes of Autoimmune Hemolytic Anemia and Its Clinical Presentation. Professional Medical Journal, 27(4), 831–835. https://doi-org.dcccd.idm.oclc.org/10.29309/TPMJ/2020.27.04.3983
Huether, S. E., & McCance, K. L. (2017). Understanding pathophysiology. St. Louis, MO: Elsevier
Kishore, S., Singh, M., Jain, B., Verma, N., Gawande, K., Kishore, S., Aggarwal, P., & Verma, S. (2020). A study to assess prevalence of anemia among beneficiaries of Anemia Mukt Bharat Campaign in Uttarakhand. Journal of Family Medicine & Primary Care, 9(3), 1691–1694. https://doi-org.dcccd.idm.oclc.org/10.4103/jfmpc.jfmpc_941_19
| Subject | Nursing | Pages | 3 | Style | APA |
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Answer
Discussion 1
I agree with the definition offered on haemolytic anaemia as a disorder which destroys red blood cells at a much faster rate than they are produced. In acquired haemolytic anaemia, there is an over activation of the process which damages the RBC membrane. In this case, the individual was not born with the condition. However, it worsened over time when the normal RBC are produced before they are destroyed. I also agree that the effect on RBC is caused by factors such as infections, blood cancers, and even autoimmune disorders. Sometimes, it tends to occur when a patient experiences severe reaction from blood transfusion. Another form is hereditary haemolytic anaemia which is passed down to children through genes. Moreover, I agree that the cause is due to the fast degeneration of the RBC once they have been produced. Their lifespan is not the same as the other normal cells.
Discussion 2
The definition of anaemia, as provided in this discussion makes sense. When the body does not have enough RBC to meet the necessary physiological needs, one is said to be anaemic. Therefore, since there are many forms, haemolytic anaemia is described as a disorder whereby the RBC’s are destroyed, thereby triggering the development of anaemia. The two identified causes are also viable, since it can either be inherited or be triggered by an underlying cause. The example of a genetic form, which is the sickle cell anaemia, has been identified. I think it is a credible example since this disorder occurs after gene mutations have taken place. Thus, the sickle cell anaemia and haemolytic anaemia are two similar disorders, sharing almost similar characteristics.
References
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Kalfa T.A. (2019) Acquired Hemolytic Anemias. In: Lazarus H., Schmaier A. (eds) Concise Guide to Hematology. Springer, Cham
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