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QUESTION
Inflammatory Bowel Disease
.Be sure to use proper sentence structure and correct grammar and spelling in your posts. Your discussion posting should be in your own words
All external references, must be cited and referenced, using APA guidelines. External sources must be current (< 5 years, Wikipedia is not acceptable A minimum word count of 125 words is required.
| Subject | Nursing | Pages | 3 | Style | APA |
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Answer
Clinical Aspects of Inflammatory Bowel Disease
Aberrant hemostasis of the immune cells at the gut mucosal border leads to inflammatory bowel disease (IBD). The following discussion provides insights into the overview, clinical aspects, and treatment of the disease.
IBD is divided into IBD unclassified (IBD-U), Ulcerative colitis (UC), and Ulcerative colitis (UC). Abnormal intestinal mucosal immune response to environmental changes gives rise to uncontrolled inflammation of intestine epithelial cell lining. The gut immune system induces immune tolerance to commensal flora, harmless food materials, and provides an appropriate response to harmful pathogens. Patients with IBD disturb the immune hemostasis exact mechanism. Alteration of nutritional habits and lifestyle is a prominent reason for increased IBD prevalence and incidence in children and adults (Nemati & Teimourian, 2017). With growing westernization and industrialization, a growing number of cases are perceptible in some countries such as China, Iraq, and India.
Diet affects the prevalence of IBD, given the fact that food enters the digestive system first. Consumption of fatty acids and sugar substances increase the prevalence to a great extent. Smokers are at a higher risk of IBD infection compared to other people. Smoking increases CD4+ cell amounts, which release interferon-gamma, an inflammatory protein activated by smoking in the lungs. The cells move to the intestine and cause inflammation (Seyedian et al., 2019). It should be eminent that fatty acids compounds consist of lactic, tartaric, citric, and acetic acid. Fish oil affects leukotrienes and cytokines (water-soluble protein molecules); thus, fish oil consumption associates with a notable decrease in IBD clinical signs.
Diarrhea, weight loss, abdominal pain, and continuous rectal bleeding are IBD symptoms, mainly in children. Risk of cancers, surgical interventions, and severe psychological disorders are also concerns linked with IBD. Various classes of drugs are available for the treatment of IBD. Steroids treat exacerbation and are limited to remission induction at diagnosis. Patients who achieve histological (deep) or endoscopic remission are likely to remain in remission. In IBD treatment, remission is the primary goal (Harlan et al., 2016). Achievement of histological remission reduces complications, improves the quality of life, and reduces hospital admissions.
In conclusion, alteration of nutritional habits and lifestyle is a prominent reason for increased IBD prevalence. Smokers are at significant risk, and the fundamental goal of IBD treatment is remission.
References
Harlan, W. R., Meyer, A., & Fisher, J. (2016). Inflammatory bowel disease: epidemiology, evaluation, treatment, and health maintenance. North Carolina Medical Journal, 77(3), 198-201.
Nemati, S., & Teimourian, S. (2017). An overview of inflammatory bowel disease: general consideration and genetic screening approach in diagnosis of early onset subsets. Middle East journal of digestive diseases, 9(2), 69.
Seyedian, S. S., Nokhostin, F., & Malamir, M. D. (2019). A review of the diagnosis, prevention, and treatment methods of inflammatory bowel disease. Journal of Medicine and Life, 12(2), 113.