“Normal” development of children

In consideration of our week’s focus, how would you generalize the impact parents/caregivers have on the “normal” development of children? Then, in consideration of the quotation above (i.e., Family-related and disease-related variables appeared to influence quality of life in children with [neurofibromatosis]), what are your thoughts? Why might the child’s quality of life be impacted by familial and disease-based variables?