The Endocrine System: Effects of Insulin in the Body

By Published on October 3, 2025
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    1. QUESTION

    The endocrine system is composed of various glands that secrete hormones. By what mechanism do they function? Give one example of a hormone and its effects on the body.
    (no internet sources)

     

     

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Subject Nursing Pages 2 Style APA
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Answer

The Endocrine System: Effects of Insulin in the Body

Hormones work binding to respective receptors followed by activation of the target cells. Lipid-soluble hormones diffuse into the cell to bind to intracellular receptors; whereas, water-soluble hormones bind on the receptors that are found on the cell (Hall, 2010). Insulin is secreted by β-cells of the islet of Langerhans in the pancreas. It is secreted when there is abundance of energy-giving foods such as carbohydrates in diet. It is secreted into blood and circulates to reach almost all cells in the body in unbounded form. The hormone has an average half-life of approximately six minutes and is cleared from circulation within 10-15 minutes. Insulin has profound effect in regulation of blood glucose and metabolism of carbohydrates in the body. Its role includes influencing storage of excess glucose in form of glycogen mainly in the muscles and liver. Extract quantities of carbohydrates, which may not be stored in form of glycogen are converted to fats under the influence insulin. Fats are then stored in the adipose tissue. In addition, insulin has a direct effect in influencing the uptake of amino acids by cells and subsequent conversion of amino acids into proteins. Insulin also has a direct effect in inhibition of protein breakdown in body cells (Hall, 2010). Besides, insulin has an inhibitory effect in secretion of glucagon, which seems to have opposing effects as that of insulin. Other functions include stimulation of gene expression and growth (Hall, 2010). Insulin increases replication of deoxyribonucleic acid as well as the rate of protein synthesis through stimulation of amino acid uptake. Fatty acid synthesis also increases with insulin secretion. Lastly, but not the least, it inhibits lipolysis and proteinolysis (Townsend et al., 2012). 

 

 

References

Hall, J. (2010). Guyton and Hall textbook of medical physiology (12th ed.). Saunders.

Townsend, C. M., Beauchamp, R. D., Evers, B. M., & Mattox, K. L. (2012). Sabiston textbook of surgery (19th ed.). Elsevier Health Sciences.

 

 

 

 

 

 

 

 

Appendix

Appendix A:

Communication Plan for an Inpatient Unit to Evaluate the Impact of Transformational Leadership Style Compared to Other Leader Styles such as Bureaucratic and Laissez-Faire Leadership in Nurse Engagement, Retention, and Team Member Satisfaction Over the Course of One Year

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